While you should always follow your prescriber’s instructions to reduce your risk, doing so does not mean you have no risk.Īdditionally, some medical conditions such as sleep apnea can further increase your risk of complications or accidental overdose. The truth is that anyone taking opioids and benzodiazepines at the same time is at increased risk of overdose. People may believe they are not at risk if they follow their prescriber’s instructions, take small doses, are not addicted to or dependent on opioids, or if they have taken these medicines for a long time. There are some common misconceptions people may have about their risk of overdose. Research cited by the National Institutes of Health showed that the overdose death rate in patients taking both medications was 10 times higher than in those only taking opioids. This could cause an accidental overdose, which may result in death. Taking opioids and benzodiazepines at the same time may cause heavy drowsiness, slow your breathing, or stop your breathing entirely. Why is it risky to take opioids and benzodiazepines at the same time? ![]() If you are taking opioids and benzodiazepines at the same time, be sure to learn the steps you can take to reduce your risk. However, your doctor may determine that this is the best course of action for your particular situation.īe sure to accurately report all medications you’re taking so your doctor can advise you and monitor your safety. ![]() Some examples of benzodiazepines include alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), and lorazepam (Ativan).Īt HSS, we do not generally advise patients to take benzodiazepines and opioids at the same time. Taking these medications together can put you at risk.īenzodiazepines are a type of sedative medication commonly prescribed to treat anxiety or insomnia, but they can also be prescribed to treat panic disorders, seizures, or muscle spasms. If you already take a benzodiazepine to treat a chronic condition and will need to simultaneously take an opioid for any period of time, you should be aware of important safety information.
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